The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. ex. Some numerals are expressed as "XNUMX".
Copyrights notice
The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. Copyrights notice
A incorporação de uma ferramenta para administração de medicamentos, como uma seringa, é necessária em microagulhas (MNs) para uso médico. Isso torna mais fácil para o pessoal não médico administrar medicamentos. Porque é difícil fabricar um MN oco, fabricamos um sulco capilar num MN e no seu substrato para permitir a administração de uma dosagem mais elevada. A ranhura MN é difícil de realizar através do método convencional de moldagem por injeção usado para ácido polilático. Portanto, o anidrido poliácido biodegradável foi selecionado como material para o MN. Como o anidrido poliácido é um líquido de baixa viscosidade à temperatura ambiente, um MN pode ser ranhurado usando um método de processamento semelhante à fundição a vácuo. Este estudo investigou o desempenho da força capilar do MN e a forma e tamanho ideais do MN por meio de um teste de punção.
Satomitsu IMAI
Nihon University
Kazuki CHIDAISYO
Nihon University
Kosuke YASUDA
Nihon University
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Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, "Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer" in IEICE TRANSACTIONS on Electronics,
vol. E106-C, no. 6, pp. 248-252, June 2023, doi: 10.1587/transele.2022OMS0005.
Abstract: Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/transele.2022OMS0005/_p
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@ARTICLE{e106-c_6_248,
author={Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, },
journal={IEICE TRANSACTIONS on Electronics},
title={Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer},
year={2023},
volume={E106-C},
number={6},
pages={248-252},
abstract={Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.},
keywords={},
doi={10.1587/transele.2022OMS0005},
ISSN={1745-1353},
month={June},}
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TY - JOUR
TI - Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer
T2 - IEICE TRANSACTIONS on Electronics
SP - 248
EP - 252
AU - Satomitsu IMAI
AU - Kazuki CHIDAISYO
AU - Kosuke YASUDA
PY - 2023
DO - 10.1587/transele.2022OMS0005
JO - IEICE TRANSACTIONS on Electronics
SN - 1745-1353
VL - E106-C
IS - 6
JA - IEICE TRANSACTIONS on Electronics
Y1 - June 2023
AB - Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
ER -